📄 Category

hiv aids

65 papers

HIV/AIDS research remains a critical frontier in global health, focusing on everything from understanding how the virus interacts with the human immune system to developing new treatments and vaccines. This field is constantly evolving, with scientists working tirelessly to improve patient outcomes and move closer to a functional cure. Because these discoveries happen rapidly, staying updated with the latest findings is essential for both experts and the public.

At Gist.Science, we bridge the gap between complex research and clear understanding by processing every new preprint in this category directly from medRxiv. We transform these dense scientific documents into both plain-language explanations and detailed technical summaries, ensuring that the latest insights into HIV and AIDS are accessible to everyone. Below are the most recent papers we have analyzed, offering a fresh look at the ongoing fight against the virus.

📄 hiv aids

Determinants of HIV Testing Uptake Among Adolescent Girls and Young Women in Mainland Tanzania: A Stratified Analysis of the 2016/17 and 2022/2023 National Surveys

This study analyzes 2016/17 and 2022/23 national survey data to reveal that while HIV testing uptake among young women in mainland Tanzania increased from 86% to 90%, it stagnated at 40% for adolescents, with consistent determinants including union status, higher education, and STI history, underscoring the need for age-specific intervention strategies.

Kinoko, D. W., Kavindi, A. C., Yuda, P., Tibenderana, J. R., Nyaki, A. Y., Msuya, S. E., Mahade, M. J.2026-02-16
📄 hiv aids

Pharmacokinetics, pharmacodynamics, efficacy and drug resistance selection of injectable long-acting lenacapavir pre-exposure prophylaxis (PrEP) against HIV

This study utilizes an integrated pharmacokinetic-pharmacodynamic model to demonstrate that twice-yearly injectable lenacapavir achieves sustained protective concentrations against wild-type HIV and specific drug-resistant mutants, while also highlighting the risk of de novo resistance emergence upon discontinuation and the need for strategies to manage PrEP cessation.

Kim, H.-y., Liebenberg, A., Zhang, L., Von Kleist, M.2026-02-06
📄 hiv aids

Comparing modelled HIV incidence estimates with empirical HIV incidence observations in high-burden HIV African epidemic settings: systematic review and meta-regression

This systematic review and meta-regression confirms that mathematical models used by UNAIDS accurately reflect the declining incidence levels and trends observed in population-representative studies across sub-Saharan Africa, though they fail to capture the epidemic's aging pattern and significantly underestimate incidence in non-representative groups such as pregnant women and key populations.

Stevens, O., Moffa, M., Hunt, J. H., Patel, K., Aytenfisu, T., Akullian, A., Anderson, R. L., Bock, P., Gregson, S., Hay (…)2026-02-05
📄 hiv aids

Establishing an empirical cut-off on the 12-item Brief Berger HIV Stigma Scale to screen psychosocial vulnerability among PLHIV in Nigeria

This study establishes a validated cut-off score of ≥30 on the 12-item Brief Berger HIV Stigma Scale as a sensitive screening tool for identifying psychosocial vulnerability among people living with HIV in Nigeria, revealing that concerns about public attitudes are a stronger predictor of vulnerability than internalized stigma.

Abdulraheem, K. S., Onajole, A. T., Roberts, A. A., Olowoopejo, T.2026-01-20